Off-label, on-demand: The problems with drug delivery start-ups
New prescription drug delivery start-ups are bypassing the FDA's regulations on off-label marketing. More
New prescription drug delivery start-ups are bypassing the FDA's regulations on off-label marketing. More
We are living in the age of prescription drugs. They can turn once-fatal diseases into manageable, chronic conditions. But especially for older adults, many of whom take five or more medications each day, they can cause illness or even death. More
The drive to prescribe will contribute to the premature deaths of 150,000 older Americans in the next decade. More
March 30-31 was a milestone in the Lown Medication Overload project, when 30 working group members came to Boston to discuss strategies for reducing medication overload. Here's what we talked about! More
Gabapentinoids like Neurontin and Lyrica are often prescribed for off-label uses. But does the evidence support this treatment? More
High drug prices have been a hot topic in politics recently, but there's another reason that our country spends so much on drug costs, write Shannon Brownlee and Judith Garber in Stat News. More
In a new report, the Lown Institute calls for a national action plan to address overprescribing. More
The pharmaceutical industry has followed a brilliant two-pronged strategy to maximize its profits: raise prices and increase consumption of medications. Most of the attention has focused on just one side of the equation — prices. With politicians and advocates on both sides of the aisle vowing to lower drug prices, few people are talking about Americans being overprescribed medications, which not only adds to the cost of drugs but also harms millions of Americans each year. More
In this report, the Lown Institute calls for the development of a national strategy to address medication overload and help older people avoid its devastating effects on the quality and length of their lives. This is the full report (an executive summary is also available). Suggested Citation: Garber, J., and Brownlee, S. Medication Overload: America's Other Drug Problem. Brookline, MA: The Lown Institute. 2019 DOI: https://doi.org/10.46241/LI.WOUK3548 More
This is the executive summary of a report by the Lown Institute that calls for the development of a national strategy to address medication overload and help older people avoid its devastating effects on the quality and length of their lives. More
In two pieces published recently in JAMA, researchers identify important issues in cardiology guidelines, including the lack of clarity in summary statements and a worsening evidence base. More
What does it mean to be a "medical conservative"? These doctors explain why it's important to be skeptical about new medical advances until unbiased and high-quality evidence shows a clear benefit. More
In the newest edition of the American Family Physician, members of the Right Care Alliance Children's Health Council present their final list of top "Do's and Don'ts" for preventing both overuse and underuse in pediatrics. More
For conditions like mild hypertension, that depend a lot of patient behavior outside the clinic, adherence rates are typically very low. The newest piece in the Right Care Series gives physicians tips on how they can improve patient engagement. More
In a new commentary, Dr. Vinay Prasad and colleagues use a thought experiment to explain why cancer screening programs have to consider the harms as well as the benefits. More
When a patient in the hospital has elevated blood pressure, but no other symptoms related to a hypertensive emergency, what should be the course of action? More
A new primary care model to encourage telehealth visits could be a step in the right direction, but also raises questions about provider burden. More
Should we be worried about projected increases in health care spending? Or is it just the price we pay for better health? More
The pediatric field has been slower to recognize the problem of overuse, in part because there is less evidence available on overused services. A new review seeks to highlight studies that are filling these gaps in the research. More
As the powerful depression drug esketamine nearly FDA approval, some researchers are concerned that the approval would be lowering the bar for clinical evidence. More