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From assisted hatching to embryo glue, most IVF ‘add-ons’ rest on shaky science, studies find

In the 40 years since the world’s first “test tube baby,” fertility clinics have cooked up nearly three dozen such “add-ons,” or supplementary procedures. Like immune therapy for supposed genetic incompatibility, they’re not essential to IVF. Instead, clinics offer procedures such as “assisted hatching” and “embryo glue” and “uterine artery vasodilation” as purportedly science-based options that increase the chance of having a baby. Except there is little to no evidence that the vast majority of IVF add-ons do any such thing, conclude four papers published on Tuesday in Fertility and Sterility, the journal of the American Society for Reproductive Medicine. More

The ‘cancer growing in cancer medicine’: pharma money paid to doctors

Americans are rightly furious about the high and unsustainable price of cancer drugs, which now routinely cost more than $100,000 per year of therapy. Those prices are made worse by the fact that most cancer drugs offer only modest benefits — one study put the median benefit at 2.1 extra months of life — along with the fact that expert physicians frequently recommend these drugs for off-label uses, meaning using a drug for a purpose it was not initially approved for. More

Advice to Give Women Blood Thinners After C-Sections Draws Fire

Doctors are criticizing a recent recommendation from medical experts to give blood-thinning drugs to nearly all women who give birth by caesarean section, saying the advice may be unsafe and tainted by potential conflicts of interest. “This is basically an experiment being done on new moms,” said Adam Urato, chief of maternal fetal medicine at MetroWest Medical Center in Framingham, Mass., said in an interview. More

Shkreli Awards

Lown Institute’s top ten list of the worst examples of profiteering and dysfunction in health care, named for Martin Shkreli, the price-hiking “pharma bro” that everyone loves to hate. More

Purdue bankruptcy settlement not enough, AG Healey, former addicts say

Recovering addicts who say Purdue Pharma got them hooked on opioids are turning their heads at the company’s bankruptcy deal. Dr. Vikas Saini, president of the Lown Institute and co-chairman of the Right Care Alliance, said measuring dollars against human lives isn’t fair. “Both Purdue and the Sacklers are really kind of dodging what the truth is here,” said Saini. “They deserve to face real justice and honestly I don’t think real justice is about the money.” More