REPORT – Medication Overload: How the drive to prescribe is harming older Americans

+SHARE

The United States is in the grips of an unseen epidemic of harm from the excessive prescribing of medications. If nothing is done to change current practices, medication overload will contribute to the premature deaths of 150,000 older Americans over the next decade and reduce the quality of life for millions more. 

Focusing on reducing inappropriate or unnecessary medications could save as much as $62 billion over the next decade in unnecessary hospitalization for older adults alone.

Scope of Medication Overload

Every day, 750 older people living in the United States (age 65 and older) are hospitalized due to serious side effects from one or more medications. Over the last decade, older people sought medical treatment more than 35 million times for adverse drug events, and there were more than 2 million hospital admissions.

The prescribing of multiple medications to individual patients (called “polypharmacy” in the scientific literature) has reached epidemic proportions. More than four in ten older adults take five or more prescription medications a day, tripling over the past two decades. Nearly 20 percent take ten drugs or more.

5 million older adults sought medical attention for ADEs in 2018
42% of older adults take 5 or more prescription medications
There was a 200% increase in polypharmacy over 20 years
750 hospitalizations every day due to ADEs in older adults
$62 billion in unnecessary hospitalizations over 10 years
150,000 premature deaths in next 10 years due to ADEs

Drivers of Medication Overload

A broad array of forces is at work, with three overarching aspects of our health care system contributing to the epidemic:

Culture of Prescribing – Advertisements linking prescription medications to happiness and health, the increased medicalization of normal human aging, the hurried pace of medical care, and the desire of both health care professionals and patients to “do something” have fostered a shared expectation that there is a “pill for every ill.”

Information & Knowledge Gaps – Clinicians and patients lack critical information and skills they need to appraise the evidence and make informed decisions regarding medications.

Fragmentation of Care – There is a pervasive lack of communication between a patient’s various providers. Often, more prescriptions are written to treat what appears to be a new condition, when in reality prescribers are treating a side effect of another drug. This “prescribing cascade” can lead to a cycle of debilitation and even death.

A week’s worth of medication for a 92-year old patient, before and after deprescribing.

The Costs of Medication Overload

Reducing inappropriate or unnecessary medications could save as much as $62 billion over the next decade in unnecessary hospitalizations for older adults alone. As a nation, we would also save billions more on the cost of unnecessary drugs and visits to the emergency room and outpatient clinics. More importantly, successfully tackling medication overload holds the promise of lessening disability, cognitive decline, and hospitalizations for patients. And that translates into better lives for millions of people.

Authors and Workgroups

The report was co-authored by Shannon Brownlee and Judith Garber. The Lown team has been working extensively with several working groups consisting of patients, doctors, nurses, advocates, researchers, and pharmacists. Groups began meeting in July 2018 and will continue to meet through early 2020 when the National Action Plan for Addressing Medication Overload will be published.

Members of the Medication Overload workgroups attended a two-day meeting at the Lown Institute in late March 2019.

In the News

Press Release

Our press release page also includes an audio recording of our press conference.

Media hits


Support for this research was provided by the Gordon and Betty Moore Foundation.